HPLC + MS
Independently tested for identity and purity
NP-SLU332-02
Aug 13, 2026
99.91%
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CAS# 303760-60-3
Target Pan-ERR Agonist
Class Synthetic Small Molecule
Form Powder
Receptor Target
Receptor Target
Receptor Target
SLU-PP-332 (CAS# 303760-60-3) is a synthetic small molecule compound classified as a pan-agonist of the estrogen-related receptors ERRα, ERRβ, and ERRγ — nuclear receptors involved in mitochondrial biogenesis and oxidative metabolism research. Originally developed at Saint Louis University, it is studied as a pharmacological tool for investigating ERR-dependent transcriptional programs in metabolic and exercise biology research models. Supplied by NexPept as a powder for in vitro laboratory research use. This compound has not been authorized by Health Canada for any therapeutic, clinical, or human use.
Molecular Profile
CAS#, compound class, receptor targets, analytical data
CAS#, compound class, receptor targets, analytical data
| Property | Value |
|---|---|
| CAS Number | 303760-60-3 |
| Developer | Saint Louis University (SLU) |
| Compound Class | Synthetic small molecule — pan-ERR nuclear receptor agonist |
| Receptor Targets | ERRα (NR3B1), ERRβ (NR3B2), ERRγ (NR3B3) |
| Receptor Family | Estrogen-Related Receptors (ERRs) — orphan nuclear receptors |
| Physical Form | Powder |
| Analytical Method | High-Performance Liquid Chromatography (HPLC) + Mass Spectrometry (MS) |
| Appearance | White to off-white solid |
| Purity | ≥98% by HPLC |
In Vitro Research Context
Receptor pharmacology — laboratory use only
Receptor pharmacology — laboratory use only
NR3B1 — mitochondrial biogenesis and fatty acid oxidation transcriptional regulation.
NR3B2 — oxidative phosphorylation and energy metabolism pathway studies.
NR3B3 — cardiac and skeletal muscle metabolic gene expression research.
SLU-PP-332 is studied in preclinical in vitro settings as a pharmacological tool for investigating simultaneous agonism across all three estrogen-related receptor subtypes. The ERRs are orphan nuclear receptors that regulate transcriptional programs associated with mitochondrial function, oxidative metabolism, and energy expenditure. Research applications include reporter gene assays, ERR-PGC-1α coactivator interaction studies, transcriptomic analysis of metabolic gene networks, and cell-based models of mitochondrial biogenesis. As a pan-ERR agonist, SLU-PP-332 is used in controlled laboratory settings to study the downstream effects of ERR activation on metabolic pathway gene expression.
Research context: SLU-PP-332 is an investigational compound studied in scientific research involving ERRα, ERRβ, and ERRγ nuclear receptor signalling and metabolic transcriptional programs. Research into this compound remains ongoing. It has not been authorized by Health Canada for human or veterinary use.
Available Formats
5mg — powder
5mg — powder
| Format | Net Quantity | Physical Form |
|---|---|---|
| SLU-PP-332 5mg | 5 mg / vial | Powder |
Selection should be based on the quantity required for your specific in vitro research protocol as determined by qualified research personnel.
Laboratory Storage
Controlled storage conditions for powder material
Controlled storage conditions for powder material
Store sealed material under controlled laboratory conditions in accordance with validated institutional SOPs and applicable technical documentation. Protect from light and moisture. Handling conditions should be established by qualified research personnel in accordance with the specific experimental protocol.
Note: No preparation, reconstitution, or administration instructions are provided. This compound is supplied for in vitro laboratory research use only. All handling must be conducted by qualified personnel following institutional safety protocols.
Research Literature
Scientific references & related resources
Scientific references & related resources
PubMed — SLU-PP-332 / Pan-ERR Agonist — peer-reviewed scientific literature on this compound
PubMed — ERR Nuclear Receptor Research — ERRα/β/γ pharmacology and metabolic pathway literature
Research Compounds in Canada — sourcing and research context for Canadian laboratories
What Are Research Peptides? — compound classification and in vitro research context
This product is supplied exclusively for in vitro laboratory and non-clinical research use by qualified research personnel. It is not authorized by Health Canada for human or veterinary use. No therapeutic, clinical, or health claims are made.
This material must not be administered to humans or animals. No dosage, preparation, reconstitution, or administration instructions are provided or implied. All handling and use must be conducted by qualified personnel in accordance with applicable institutional policies and legal requirements.
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