HPLC + MS
Independently tested for identity and purity
NP-BPCTB-002
Jul 2, 2026
99.93%
View Certificate of Analysis
CAS# 137525-51-0 / 77591-33-4
Class Dual-Component Cellular Signalling Research Blend
Form Lyophilized Powder
Blend Type
Per Component
Total per Vial
BPC-157
Body Protection Compound-157 · CAS# 137525-51-0
15 AA · 1419.5 Da · Gastric Pentadecapeptide
TB-500
Thymosin Beta-4 (Synthetic) · CAS# 77591-33-4
43 AA · ~4964 Da · Thymic Peptide
The BPC-157 / TB-500 blend is a dual-component lyophilized research formulation combining two structurally distinct synthetic peptides studied across overlapping and complementary in vitro cellular signalling research contexts. BPC-157 (Body Protection Compound-157, CAS# 137525-51-0) is a synthetic 15-amino-acid pentadecapeptide of gastric origin studied for cellular signalling, angiogenesis pathway models, and gastrointestinal cellular research. TB-500 (Thymosin Beta-4, CAS# 77591-33-4) is a synthetic 43-amino-acid thymic peptide studied for actin sequestration biology, cellular migration assays, and angiogenesis pathway models. Each vial contains 5mg of each component for 10mg total. Supplied by NexPept as a lyophilized powder for in vitro laboratory research use. Neither component has been authorized by Health Canada for any therapeutic, clinical, or human use.
Molecular Profile
CAS#, sequences, molecular weights, analytical data
CAS#, sequences, molecular weights, analytical data
Component 1 — BPC-157
| Property | Value |
|---|---|
| CAS Number | 137525-51-0 |
| Full Name | Body Protection Compound-157 |
| Compound Class | Synthetic gastric pentadecapeptide |
| Sequence Length | 15 amino acids |
| Molecular Weight | 1419.5 Da |
| Peptide Origin | Partial sequence derived from human gastric juice protein |
| Quantity per Vial | 5 mg |
Component 2 — TB-500 (Thymosin Beta-4)
| Property | Value |
|---|---|
| CAS Number | 77591-33-4 |
| Full Name | Thymosin Beta-4 (synthetic); TB-500 |
| Compound Class | Synthetic thymic peptide — G-actin sequestering protein |
| Sequence Length | 43 amino acids |
| Molecular Weight | ~4964 Da |
| Key Motif | LKKTET actin-binding sequence (residues 17–22) — central to G-actin sequestration activity in cellular models |
| Peptide Origin | Endogenous thymic peptide; abundant in platelets, wound fluid, and immune cells |
| Quantity per Vial | 5 mg |
Blend specification: Both components are co-lyophilized in a single vial. Total peptide content is 10mg (5mg BPC-157 + 5mg TB-500). Purity verified by HPLC and Mass Spectrometry for each component batch.
In Vitro Research Context
Dual-component cellular signalling — laboratory use only
Dual-component cellular signalling — laboratory use only
Cellular Signalling & Angiogenesis Pathway Research
BPC-157 is a synthetic pentadecapeptide studied in preclinical in vitro settings for its involvement in cellular signalling pathways, including FAK-paxillin signalling, nitric oxide (NO) pathway interactions, and VEGF-mediated angiogenesis models. Its gastric origin sequence has been investigated in gastrointestinal cellular protection studies and cytoskeletal remodelling assays. BPC-157 is studied as a tool compound in models examining cellular protection responses and angiogenic signalling without a defined single receptor target.
Actin Sequestration & Cellular Migration Research
Thymosin Beta-4 (TB-500) is one of the most abundant intracellular peptides in mammalian cells and functions as the primary G-actin sequestering protein. Its central LKKTET motif (residues 17–22) binds monomeric G-actin, regulating actin polymerisation dynamics. In vitro, TB-500 is studied in the context of actin cytoskeleton research, cell migration scratch assays, angiogenesis pathway models (including endothelial tube formation assays), and ECM interaction studies. It also interacts with the ILK (integrin-linked kinase) pathway in cellular models.
This blend is studied in preclinical in vitro settings for the complementary cellular signalling profiles of its two components. BPC-157 and TB-500 share research relevance in angiogenesis pathway models and cellular signalling studies while each contributing distinct mechanistic angles — BPC-157 via nitric oxide and FAK/paxillin pathways, and TB-500 via actin dynamics and ILK/integrin signalling — making the combination a relevant tool for multi-pathway cellular research designs.
Research context: This is a dual-component investigational peptide blend studied for complementary cellular signalling activity in angiogenesis, actin biology, and cellular protection pathway models. Neither component has been authorized by Health Canada for human or veterinary use.
Available Formats
5mg / 5mg blend — 10mg total, lyophilized powder
5mg / 5mg blend — 10mg total, lyophilized powder
| Component | Quantity | Physical Form |
|---|---|---|
| BPC-157 | 5 mg / vial | Lyophilized powder (co-lyophilized blend) |
| TB-500 (Thymosin Beta-4) | 5 mg / vial | Lyophilized powder (co-lyophilized blend) |
| Total per Vial | 10 mg | — |
Sourced from a verified batch. Quantity for use should be determined based on your specific in vitro research protocol by qualified research personnel.
Laboratory Storage
Controlled storage conditions for lyophilized blend
Controlled storage conditions for lyophilized blend
Store sealed lyophilized blend material under controlled laboratory conditions in accordance with validated institutional SOPs and applicable technical documentation. Protect from light and moisture. As a co-lyophilized multi-peptide blend, storage conditions should account for the stability requirements of both components. Handling conditions should be established by qualified research personnel in accordance with the specific experimental protocol.
Note: No preparation, reconstitution, or administration instructions are provided. This compound is supplied for in vitro laboratory research use only. All handling must be conducted by qualified personnel following institutional safety protocols.
Research Literature
Scientific references & related resources
Scientific references & related resources
Healing Blend Research Peptide Overview — NexPept dual-compound overview and in vitro research context
PubMed — BPC-157 — peer-reviewed literature on BPC-157 cellular signalling research
PubMed — Thymosin Beta-4 / TB-500 — peer-reviewed literature on actin sequestration and angiogenesis pathway research
Research Peptides in Canada — sourcing and research context for Canadian laboratories
What Are Research Peptides? — peptide classification and in vitro research context
This product is supplied exclusively for in vitro laboratory and non-clinical research use by qualified research personnel. Neither component is authorized by Health Canada for human or veterinary use. No therapeutic, clinical, or health claims are made.
This material must not be administered to humans or animals. No dosage, preparation, reconstitution, or administration instructions are provided or implied. All handling and use must be conducted by qualified personnel in accordance with applicable institutional policies and legal requirements.
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